Chronic non-specific Ulcerative Colitis (CIUC)


Chronic idiopathic ulcerative colitis (CIUC) is one of the two inflammatory diseases of the intestine (the other is known as Crohn’s disease).

This disease affects both sexes and its origin as its name indicates is unknown, although its main factor is that of being a hereditary disease (there is usually no direct inheritance from father to son, if not coming from several previous generations, including many sometimes it is unknown who suffered it previously).

Symptoms of the disease can begin at any age, predominantly in the final years of adolescence and young adults (16 to 30 years is the highest frequency peak).

The main symptoms are frequent diarrheal stools during the day, most of them accompanied by mucus and in more advanced cases of evacuations with fresh blood, without any pain or another discomfort present.

The patient tends to have anemia secondary to bleeding.

The disease can affect the colon (large intestine) globally or segmentally, with the segment of the colon most frequently affected the rectum and sigmoid, which are closest to the anal region, therefore, the presence of blood and mucus.

The basic difference with Crohn’s disease is that the latter mainly affects the small intestine in its last portion (terminal ileitis) and occasionally affects the colon. The CIUC only affects the colon.

The diagnosis is made by an endoscopic study (colonoscopy), where we find different findings depending on the severity of the disease, from superficial hyperemia (redness of the colon mucosa) to the presence of multiple ulcers, a formation of lesions such as inflammatory pseudopolyps, etc

The biopsy of the injured mucosa gives us the histopathological confirmation of the diagnosis.

It is important to note that it is a disease that has no cure, but when a diagnosis is made, management begins and in the greater percentage of cases it is possible to control and remit the lesions and symptoms with medication.

The follow-up is permanent and the doses of medication are decreasing and adapting according to the evolution of each case.

If you or any of your relatives suffer from this disease, you can go with a server for diagnosis, management, and monitoring, if you have any questions, please contact me, I am at your service to resolve it.